P1727Investigation of P-wave dispersion in adult patients with beta-thalassemia major

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P-wave Dispersion in Patients with Major Thalassemia

Abstract Background Prolonged P-wave duration and P-wave dispersion indicate interatrial conduction disturbance and early predict arrhythmia especially atrial fibrillation. Iron deposition in the atrial tissue might prolonged the atrial conduction time, and this study evaluated the P-wave prolongation and increased P-Wave dispersion in these patients. Materials and Methods Fifty patients w...

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p-wave dispersion in patients with major thalassemia

abstract background prolonged p-wave duration and p-wave dispersion indicate interatrial conduction disturbance and early predict arrhythmia especially atrial fibrillation. iron deposition in the atrial tissue might prolonged the atrial conduction time, and this study evaluated the p-wave prolongation and increased p-wave dispersion in these patients. materials and methods fifty patients with m...

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Cytokine Gene Polymorphisms in Iranian Patients with Beta-Thalassemia Major

Background: β-thalassemia as a hereditary disease is defined as defective synthesis of   β-globin chains, resulting in erythropoiesis abnormalities and severe anemia. Different studies have shown that cytokines and cytokine gene polymorphisms play a major role in the pathogenesis of   β-thalassemia. Single nucleotide polymorphisms (SNPs) within the promoter region or other regulatory sequences ...

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Hypoparathyroidism in adult patients with Beta-thalassemia major.

OBJECTIVE To evaluate the prevalence of hypoparathyroidism in adult transfusion-dependent patients with beta-thalassemia major in a teaching referral hospital in Oman. METHODS All adult (>13 years) patients with beta-thalassemia major seen at Royal Hospital in Oman between 2004 and 2006 were studied. Demographic, pharmaceutical, clinical and biochemical data were collected for all the subject...

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Endocrine Disorders in Beta thalassemia Major Patients

Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2017

ISSN: 0195-668X,1522-9645

DOI: 10.1093/eurheartj/ehx502.p1727